Research Library

Browse all evidence-based content: herbs, supplements, conditions, and clinical topics. Use the filter to narrow by content type.

Clinical Topics
Evidence B+

Aging & Longevity

Longevity science has advanced dramatically, identifying cellular mechanisms of aging including telomere shortening, epigenetic ch...

Moderate Updated March 1, 2025
Herb Research
Evidence B+

Ashwagandha

Ashwagandha is an adaptogenic herb with the strongest clinical evidence for reducing perceived stress, lowering cortisol, and impr...

Moderate Updated March 1, 2025
Disease Research
Evidence B+

Autoimmune Disorders

Autoimmune disorders involve immune system dysregulation where the body attacks its own tissues. Over 80 recognized conditions aff...

Moderate Updated March 1, 2025
Herb Research
Evidence A

Berberine

Berberine is an alkaloid compound found in barberry, goldenseal, and Oregon grape with some of the strongest human clinical eviden...

Strong Updated March 1, 2025
Herb Research
Evidence B+

Boswellia

Boswellia serrata (Indian frankincense) is a resin with clinically demonstrated anti-inflammatory effects, particularly for joint ...

Moderate Updated March 1, 2025
Disease Research
Evidence A-

Chronic Inflammation

Chronic low-grade inflammation underlies most major diseases including cardiovascular disease, type 2 diabetes, cancer, and neurod...

Moderate Updated March 1, 2025
Supplement Science
Evidence B+

CoQ10 (Coenzyme Q10)

CoQ10 is an endogenous antioxidant and critical component of mitochondrial energy production. Evidence supports supplementation fo...

Moderate Updated March 1, 2025
Herb Research
Evidence A-

Curcumin

Curcumin is the primary bioactive compound in turmeric with extensive research on anti-inflammatory and antioxidant effects. Multi...

Moderate Updated March 1, 2025
Herb Research
Evidence B+

Echinacea

Echinacea is one of the most widely used herbs for immune support, with a large clinical evidence base. Meta-analyses suggest mode...

Moderate Updated March 1, 2025
Clinical Topics
Evidence A

Gut Health

Gut health encompasses intestinal barrier integrity, gut microbiome diversity, digestive function, and gut-brain axis communicatio...

Strong Updated March 1, 2025
Clinical Topics
Evidence B+

Immune Modulation

Immune modulation refers to the regulation of immune responses - either stimulating immune activity (in infection vulnerability or...

Moderate Updated March 1, 2025
Disease Research
Evidence A-

Irritable Bowel Syndrome (IBS)

IBS is a functional gastrointestinal disorder affecting 10-15% of the population. Multiple natural approaches have clinical eviden...

Moderate Updated March 1, 2025
Herb Research
Evidence B

Japanese Knotweed

Japanese knotweed is the richest natural source of resveratrol and has gained attention primarily in Lyme disease integrative trea...

Preliminary Updated March 1, 2025
Disease Research
Evidence B

Long COVID (Post-COVID Syndrome)

Long COVID (post-COVID syndrome) refers to symptoms persisting 12 or more weeks after acute COVID-19 infection. Research is rapidl...

Preliminary Updated March 1, 2025
Disease Research
Evidence B

Lyme Disease

Lyme disease is a tick-borne bacterial infection caused by Borrelia burgdorferi. Standard treatment is antibiotic therapy and is h...

Preliminary Updated March 1, 2025
Supplement Science
Evidence A-

Magnesium

Magnesium is an essential mineral cofactor in over 300 enzymatic reactions. Suboptimal intake is extremely common in Western popul...

Strong Updated March 1, 2025
Clinical Topics
Evidence B+

Mitochondrial Health

Mitochondria are the primary energy-producing organelles of every cell. Mitochondrial dysfunction is increasingly recognized as a ...

Moderate Updated March 1, 2025
Supplement Science
Evidence B+

NAC (N-Acetylcysteine)

NAC (N-acetylcysteine) is a precursor to glutathione, the body's primary endogenous antioxidant. FDA-approved as a pharmaceutical ...

Moderate Updated March 1, 2025
Supplement Science
Evidence A

Omega-3 Fatty Acids

Omega-3 fatty acids (EPA and DHA) have some of the strongest evidence among supplements for cardiovascular risk reduction, triglyc...

Strong Updated March 1, 2025
Supplement Science
Evidence A-

Probiotics

Probiotics are live microorganisms with a large and growing evidence base. Strongest evidence supports use for antibiotic-associat...

Moderate Updated March 1, 2025